Human IL-16 Protein

Size

£599.00

SKU:: PME30006
Additional Names:: Pro-Interleukin-16;Interleukin-16;IL-16;Lymphocyte Chemoattractant Factor;LCF;IL16
Molecular Weight:: 13.4 KDa
Purity:: Greater than 95% as determined by reducing SDS-PAGE.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH 7.0.
Target:: IL-16
Not available:: Not available
Extra Details:: Interleukin-16 (IL-16) is a CD8 T cell-derived cytokine that induces chemotaxis of CD4 T cells and CD4 monocytes and eosinophils. Analysis by gel filtration suggests that; under physiological conditions; human IL-16 exists predominantly as a noncovalently linked multimer; but that some IL-16 may exist as a monomer. However; only the multimeric form appears to possess chemotactic activity; suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 T cells. Human and murine IL-16 show significant cross-species reactivity.