PME101917
Human GPR161 Protein; hFc Tag
Size
£189.00
- SKU:
- PME101917
- Additional Names:
- GPCR161; G protein-coupled receptor 161
- Molecular Weight:
- The protein has a predicted molecular mass of 29.3 kDa after removal of the signal peptide.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- GPR161
- GPR161(Met1-Gln30) hFc(Glu99-Ala330):
- GPR161(Met1-Gln30) hFc(Glu99-Ala330)
- Extra Details:
- GPR161 (G protein-coupled receptor 161) is a G-protein coupled receptor (GPCR) involved in Hedgehog signaling regulation and primary cilia function. It primarily couples to Gs proteins; activating adenylyl cyclase and elevating intracellular cAMP. GPR161 is expressed in developing tissues and the central nervous system; where it modulates embryonic development; cell proliferation; and tissue patterning. Mutations or dysregulation of GPR161 are associated with developmental disorders and ciliopathies; making it a relevant target for developmental biology and disease research.
- Shipping Conditions:
- Ambient