Human GPR18 Protein; hFc Tag

Size

£189.00

SKU:: PME101914
Additional Names:: R518; GPCR18; G protein-coupled receptor 18
Molecular Weight:: The protein has a predicted molecular mass of 28.7 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: GPR18
GPR18(Met1-Lys22) hFc(Glu99-Ala330):: GPR18(Met1-Lys22) hFc(Glu99-Ala330)
Extra Details:: GPR18 (G protein-coupled receptor 18) is a G-protein coupled receptor (GPCR) expressed in immune cells; brain; and peripheral tissues. It couples to Gi/o proteins; modulating cAMP levels; intracellular calcium; and MAPK signaling pathways. GPR18 is involved in immune regulation; inflammation; and cell migration; and has been implicated in cardiovascular; neurological; and metabolic processes. It is considered a potential therapeutic target for immune-related disorders; inflammation; and cancer.