Human DRD4 Protein; hFc Tag

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£189.00

SKU:: PME101909
Additional Names:: DRD4; D4R; Dopamine receptor D4; Dopamine D4 receptor; D4
Molecular Weight:: The protein has a predicted molecular mass of 28.7 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: DRD4
DRD4(Met1-Gly29) hFc(Glu99-Ala330):: DRD4(Met1-Gly29) hFc(Glu99-Ala330)
Extra Details:: DRD4 (Dopamine receptor D4) is a G-protein coupled receptor (GPCR) that primarily couples to Gi/o proteins; inhibiting adenylyl cyclase and reducing intracellular cAMP. It is mainly expressed in prefrontal cortex; limbic system; and retina; where it modulates cognition; attention; emotion; and behavioral flexibility. Polymorphisms in DRD4 are associated with attention-deficit hyperactivity disorder (ADHD); novelty-seeking behavior; and susceptibility to psychiatric disorders; making it a relevant therapeutic and research target in neuroscience.

Shipping Conditions:: Ambient