Human DRD3 Protein; hFc Tag

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£189.00

SKU:: PME101908
Additional Names:: DRD3; D3R; D3; Dopamine receptor D3; Dopamine D3 receptor
Molecular Weight:: The protein has a predicted molecular mass of 29.2 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: DRD3
DRD3(Met1-Ala30) hFc(Glu99-Ala330):: DRD3(Met1-Ala30) hFc(Glu99-Ala330)
Extra Details:: DRD3 (Dopamine receptor D3) is a G-protein coupled receptor (GPCR) that primarily couples to Gi/o proteins; inhibiting adenylyl cyclase and decreasing intracellular cAMP. It is predominantly expressed in the limbic regions of the brain; including the nucleus accumbens and olfactory tubercle; where it regulates reward; emotion; cognition; and motor control. DRD3 plays a role in neuropsychiatric disorders such as schizophrenia; Parkinson’s disease; and addiction; making it a potential therapeutic target for psychiatric and neurological conditions

Shipping Conditions:: Ambient