PME101897
Human OR2T12 Protein; hFc Tag
Size
£189.00
- SKU:
- PME101897
- Additional Names:
- Olfactory receptor OR1‑57; Olfactory receptor family 2 subfamily T member 12
- Molecular Weight:
- The protein has a predicted molecular mass of 28.9 kDa after removal of the signal peptide.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- OR2T12
- OR2T12(Met1-Gln23) hFc(Glu99-Ala330):
- OR2T12(Met1-Gln23) hFc(Glu99-Ala330)
- Extra Details:
- OR2T12 encodes an olfactory receptor that belongs to the G-protein coupled receptor (GPCR) superfamily and is part of the large olfactory receptor gene family responsible for odor recognition. OR2T12 is expressed in the olfactory epithelium; where it binds specific odorant molecules and couples to G olf proteins to activate adenylyl cyclase; increase cAMP; and trigger neuronal depolarization for smell perception. Like other olfactory receptors; OR2T12 is a single-exon gene encoding a 7-transmembrane domain protein. Emerging studies suggest that some olfactory receptors; including OR2T12; may also be expressed in non-olfactory tissues; potentially participating in cell signaling and chemosensory responses outside the nasal cavity.
- Shipping Conditions:
- Ambient