Human ADRB2 Protein; hFc Tag

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£189.00

SKU:: PME101887
Additional Names:: BAR; ARB2; B2AR; ADRBR; ADRB2R; BETA2AR
Molecular Weight:: The protein has a predicted molecular mass of 29.3 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: ADRB2
ADRB2(Met1-Glu30) hFc(Glu99-Ala330):: ADRB2(Met1-Glu30) hFc(Glu99-Ala330)
Extra Details:: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors; the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein; an adenylyl cyclase; cAMP-dependent kinase; and the counterbalancing phosphatase; PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene; and together; both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms; point mutations; and/or downregulation of this gene are associated with nocturnal asthma; obesity; type 2 diabetes and cardiovascular disease. [provided by RefSeq; Oct 2019]

Shipping Conditions:: Ambient