Human MMP1 Protein; His Tag

Size

£194.00

SKU:: PME101873
Additional Names:: CLG; CLGN
Molecular Weight:: The protein has a predicted molecular mass of 52.7 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: MMP1
MMP1(Phe20-Asn469) 6×His tag:: MMP1(Phe20-Asn469) 6×His tag
Extra Details:: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; and tissue remodeling; as well as in disease processes; such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens; including types I; II; and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants; at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq; Jan 2016]

Shipping Conditions:: Ambient