Human HTR2B Protein; hFc Tag

Size

£189.00

SKU:: PME101860
Additional Names:: 5-HT2B; 5-HT-2B; 5-HT(2B)
Molecular Weight:: The protein has a predicted molecular mass of 32.6 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: HTR2B
HTR2B(Met1-Trp56) hFc(Glu99-Ala330):: HTR2B(Met1-Trp56) hFc(Glu99-Ala330)
Extra Details:: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter; a hormone; and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin; including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution; designated Q20*) which blocks expression of this protein; and knockout studies in mice; suggest a role for this gene in impulsivity. However; other factors; such as elevated testosterone levels; may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq; Mar 2016]

Shipping Conditions:: Ambient