Human S1PR5 Protein; hFc Tag

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£189.00

SKU:: PME101809
Additional Names:: EDG8; S1P5; Edg-8; SPPR-1; SPPR-2
Molecular Weight:: The protein has a predicted molecular mass of 30.4 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: S1PR5
S1PR5(Met1-Asp39) hFc(Glu99-Ala330):: S1PR5(Met1-Asp39) hFc(Glu99-Ala330)
Extra Details:: The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation; apoptosis; motility; and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g.; EDG1; MIM 601974) are S1P receptors; others (e.g.; EDG2; MIM 602282) are LPA receptors.[supplied by OMIM; Mar 2008]