Human PROCR Protein; hFc Tag

Size

£194.00

SKU:: PME101764
Additional Names:: CCCA; EPCR; CCD41
Molecular Weight:: The protein has a predicted molecular mass of 48.1 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: PROCR
PROCR(Ser18-Thr209) hFc(Glu99-Ala330):: PROCR(Ser18-Thr209) hFc(Glu99-Ala330)
Extra Details:: The protein encoded by this gene is a receptor for activated protein C; a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction; as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq; Jul 2013]