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PME101720

Human NEU1 Protein; His Tag

Size

£199.00

SKU:
PME101720
Additional Names:
NEU; NANH; SIAL1
Molecular Weight:
The protein has a predicted molecular mass of 41.6 kDa after removal of the signal peptide.
Purity:
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
DIMA Biotechnology Ltd
Formulation:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
NEU1
NEU1(Glu48-Leu415) 10×His tag:
NEU1(Glu48-Leu415) 10×His tag
Extra Details:
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome; this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis; a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type); which is late-onset; or type 2 (the dysmorphic type); which occurs at an earlier age with increased severity. [provided by RefSeq; Jul 2008]
Shipping Conditions:
Ambient