PME101665
Human ACVR1B Protein; hFc Tag
Size
£199.00
- SKU:
- PME101665
- Additional Names:
- ALK4; SKR2; ACTRIB; ACVRLK4
- Molecular Weight:
- The protein has a predicted molecular mass of 37.6 kDa after removal of the signal peptide. The apparent molecular mass of ACVR1B-hFc is approximately 35-55 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- ACVR1B
- ACVR1B(Ser24-Glu126) hFc(Glu99-Ala330):
- ACVR1B(Ser24-Glu126) hFc(Glu99-Ala330)
- Extra Details:
- This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq; Jun 2010]
- Shipping Conditions:
- Ambient