Human CDH3(216-328) Protein; hFc Tag

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£171.00

SKU:: PME101613
Additional Names:: CDHP; HJMD; PCAD
Molecular Weight:: The protein has a predicted molecular mass of 38.3 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: CDH3
CDH3(Thr216-Phe328) hFc(Glu99-Ala330):: CDH3(Thr216-Phe328) hFc(Glu99-Ala330)
Extra Details:: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants; at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats; a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition; aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia; ectrodactyly; and macular dystrophy syndrome (EEMS). [provided by RefSeq; Nov 2015]

Shipping Conditions:: Ambient