Human AXL(26-92) Protein; hFc Tag

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£224.00

SKU:: PME101583
Additional Names:: ARK; UFO; AXL3; JTK11; Tyro7
Molecular Weight:: The protein has a predicted molecular mass of 33.3 kDa after removal of the signal peptide. The apparent molecular mass of AXL(26-92)-hFc is approximately 35-55 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: AXL
AXL(Ala26-Glu92) hFc(Glu99-Ala330):: AXL(Ala26-Glu92) hFc(Glu99-Ala330)
Extra Details:: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal; followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth; migration; aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses; including Marburg; Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus. [provided by RefSeq; Sep 2021]

Shipping Conditions:: Ambient