PME101549
Human APOE2 Protein; His Tag
Size
£194.00
- SKU:
- PME101549
- Additional Names:
- APOE2
- Molecular Weight:
- The protein has a predicted molecular mass of 35.0 kDa after removal of the signal peptide. The apparent molecular mass of APOE2-His is approximately 25-55 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- APOE2
- APOE2(R176C)(Lys19-His317) 6×His tag:
- APOE2(R176C)(Lys19-His317) 6×His tag
- Extra Details:
- The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor; and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia; or type III hyperlipoproteinemia (HLP III); in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq; Jun 2016]
- Shipping Conditions:
- Ambient