Human ZNRF3 Protein; hFc Tag

Size

£189.00

SKU:: PME101534
Additional Names:: RNF203; BK747E2.3
Molecular Weight:: The protein has a predicted molecular mass of 44.3 kDa after removal of the signal peptide. The apparent molecular mass of hFc-ZNRF3 is approximately 35-55 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: ZNRF3
hFc(Glu99-Ala330) ZNRF3(Lys56-Met219):: hFc(Glu99-Ala330) ZNRF3(Lys56-Met219)
Extra Details:: Enables frizzled binding activity and ubiquitin-protein transferase activity. Involved in cellular protein metabolic process and negative regulation of Wnt signaling pathway. Is integral component of plasma membrane. [provided by Alliance of Genome Resources; Apr 2022]