Human CFD Protein; His Tag

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£194.00

SKU:: PME101524
Additional Names:: DF; ADN; PFD; ADIPSIN
Molecular Weight:: The protein has a predicted molecular mass of 25.8 kDa after removal of the signal peptide. The apparent molecular mass of CFD-His is approximately 25-35 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: CFD
CFD(Ile26-Ala253) 10×His tag:: CFD(Ile26-Ala253) 10×His tag
Extra Details:: This gene encodes a member of the S1; or chymotrypsin; family of serine peptidases. This protease catalyzes the cleavage of factor B; the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine; a cell signaling protein secreted by adipocytes; which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency; which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq; Nov 2015]

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