Human PTH1R Protein; hFc Tag

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£180.00

SKU:: PME101520
Additional Names:: PFE; EKNS; PTHR; PTHR1
Molecular Weight:: The protein has a predicted molecular mass of 44.8 kDa after removal of the signal peptide. The apparent molecular mass of PTH1R-hFc is approximately 55-70 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: PTH1R
PTH1R(Asp27-Gly188) hFc(Glu99-Ala330):: PTH1R(Asp27-Gly188) hFc(Glu99-Ala330)
Extra Details:: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC); chondrodysplasia Blomstrand type (BOCD); as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq; May 2010]

Shipping Conditions:: Ambient