PME101506
Human IL1A Protein; mFc Tag
Size
£199.00
- SKU:
- PME101506
- Additional Names:
- IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha
- Molecular Weight:
- The protein has a predicted molecular mass of 44.3 kDa after removal of the signal peptide. The apparent molecular mass of IL1A-mFc is approximately 35-70 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- IL1A
- IL1A(Ser113-Ala271) mFc(Pro99-Lys330):
- IL1A(Ser113-Ala271) mFc(Pro99-Lys330)
- Extra Details:
- The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses; inflammatory processes; and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein; which is proteolytically processed and released in response to cell injury; and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq; Jul 2008]
- Shipping Conditions:
- Ambient