PME101477
Human CCL22 Protein; hFc Tag
Size
£199.00
- SKU:
- PME101477
- Additional Names:
- MDC; ABCD-1; SCYA22; STCP-1; DC/B-CK; A-152E5.1
- Molecular Weight:
- The protein has a predicted molecular mass of 34.2 kDa after removal of the signal peptide. The apparent molecular mass of CCL22-hFc is approximately 35-55 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- CCL22
- CCL22(Gly25-Gln93) hFc(Glu99-Ala330):
- CCL22(Gly25-Gln93) hFc(Glu99-Ala330)
- Extra Details:
- This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes; dendritic cells; natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils; eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq; Sep 2014]
- Shipping Conditions:
- Ambient