Human BDKRB2 Protein; hFc Tag

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£195.00

SKU:: PME101426
Additional Names:: B2R; BK2; BK-2; BKR2; BRB2
Molecular Weight:: The protein has a predicted molecular mass of 32.8 kDa after removal of the signal peptide. The apparent molecular mass of BDKRB2-hFc is approximately 35-55 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: BDKRB2
BDKRB2(Met1-Gln60) hFc(Glu99-Ala330):: BDKRB2(Met1-Gln60) hFc(Glu99-Ala330)
Extra Details:: This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation; edema; smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic conditions such as trauma and inflammation; and binds to its kinin receptors; B1 and B2. The B2 receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. [provided by RefSeq; Apr 2020]