PME101401
Human ADGRE5 Protein; His Tag
Size
£174.00
- SKU:
- PME101401
- Additional Names:
- CD97; TM7LN1
- Molecular Weight:
- The protein has a predicted molecular mass of 58.9 kDa after removal of the signal peptide.
- Purity:
- The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
- Target:
- ADGRE5
- ADGRE5(Gln21-Arg552) 6×His tag:
- ADGRE5(Gln21-Arg552) 6×His tag
- Extra Details:
- This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors; which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit; which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment; activation and migration; and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq; Jun 2011]
- Shipping Conditions:
- Ambient