Human CGRPR Protein; mFc Tag

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£174.00

SKU:: PME101376
Additional Names:: CRLR; CALCRL; LMPHM8
Molecular Weight:: The protein has a predicted molecular mass of 40.0 kDa after removal of the signal peptide. The apparent molecular mass of CGRPR-mFc is approximately 35-70 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Target:: CGRPR
CGRPR(Glu23-Asn140) mFc(Pro99-Lys330):: CGRPR(Glu23-Asn140) mFc(Pro99-Lys330)
Extra Details:: Enables adrenomedullin binding activity; adrenomedullin receptor activity; and calcitonin gene-related peptide receptor activity. Involved in several processes; including G protein-coupled receptor signaling pathway; cellular response to sucrose stimulus; and receptor internalization. Located in endoplasmic reticulum; endosome; and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema. [provided by Alliance of Genome Resources; Apr 2022]

Shipping Conditions:: Ambient