Human BCMA(22-54) Protein; mFc Tag

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£174.00

SKU:: PME101370
Additional Names:: BCM; TNFRSF17; CD269
Molecular Weight:: The protein has a predicted molecular mass of 29.6 kDa after removal of the signal peptide. The apparent molecular mass of BCMA(22-54)-mFc is approximately 25-55 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Target:: BCMA
BCMA(Ile22-Ala54) mFc(Pro99-Lys330):: BCMA(Ile22-Ala54) mFc(Pro99-Lys330)
Extra Details:: B-cell maturation protein (BCMA or BCM); is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17); which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK.