Human CFH Protein; His Tag

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£174.00

SKU:: PME101348
Additional Names:: FH;HF;HF1;HF2;HUS;FHL1;AHUS1;AMBP1;ARMD4;ARMS1;CFHL3
Molecular Weight:: The protein has a predicted molecular mass of 138.4 kDa after removal of the signal peptide. The apparent molecular mass of CFH-His is approximately 130-250 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: CFH
CFH(Glu19-Arg1231) 10×His tag:: CFH(Glu19-Arg1231) 10×His tag
Extra Details:: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation; restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. [provided by RefSeq; Oct 2011]

Shipping Conditions:: Ambient