Human EGFRVIII Protein; His Tag

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£169.00

SKU:: PME101321
Additional Names:: EGFR;ERBB;ERBB1;HER1;PIG61;mENA
Molecular Weight:: The protein has a predicted molecular mass of 39.5 kDa after removal of the signal peptide. The apparent molecular mass of EGFRVIII-His is approximately 55-100 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: EGFRVIII
EGFRVIII(Leu25-Ser645 △267aa) 6×His tag:: EGFRVIII(Leu25-Ser645 △267aa) 6×His tag
Extra Details:: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.