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PME101304

Human PAI1 Protein; His Tag

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£169.00

SKU:
PME101304
Additional Names:
PAI;PAI-1;SERPINE1;PLANH1
Molecular Weight:
The protein has a predicted molecular mass of 43.6 kDa after removal of the signal peptide. The apparent molecular mass of PAI1-His is approximately 35-55 kDa due to glycosylation.
Purity:
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
DIMA Biotechnology Ltd
Formulation:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
PAI1
PAI1(Val24-Pro402) 6×His tag:
PAI1(Val24-Pro402) 6×His tag
Extra Details:
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA); and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency); and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq; Aug 2020]
Shipping Conditions:
Ambient