Human ALPP Protein; His Tag

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£174.00

SKU:: PME101242
Additional Names:: ALP;ALPI;IAP;PALP;PLAP;PLAP-1
Molecular Weight:: The protein has a predicted molecular mass of 53.5 kDa after removal of the signal peptide. The apparent molecular mass of ALPP-His is approximately 55-70 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: ALPP
ALPP(Ile23-Thr505) 6×His tag:: ALPP(Ile23-Thr505) 6×His tag
Extra Details:: The protein encoded by this gene is an alkaline phosphatase; a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions; which are required for its enzymatic function. One of the main sources of this enzyme is the liver; and thus; it's one of several indicators of liver injury in different clinical conditions. In pregnant women; this protein is primarily expressed in placental and endometrial tissue; however; strong ectopic expression has been detected in ovarian adenocarcinoma; serous cystadenocarcinoma; and other ovarian cancer cells. [provided by RefSeq; Aug 2020]

Shipping Conditions:: Ambient