Human CLEC1B Protein; His Tag

Size

£174.00

SKU:: PME101203
Additional Names:: CLEC2;CLEC2B;PRO1384;QDED721
Molecular Weight:: The protein has a predicted molecular mass of 21.5 kDa after removal of the signal peptide. The apparent molecular mass of His-CLEC1B is approximately 25-35 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: CLEC1B
6×His tag CLEC1B(Ser55-Pro229):: 6×His tag CLEC1B(Ser55-Pro229)
Extra Details:: Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors; such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893); that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al.; 2000 [PubMed 10671229]).[supplied by OMIM; Jan 2011]