Human ANPRB Protein; His Tag

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£178.00

SKU:: PME101196
Additional Names:: AMDM;ANPb;NPR2;ECDM;GC-B;GCB;GUC2B;GUCY2B;NPRB;NPRBi;SNSK
Molecular Weight:: The protein has a predicted molecular mass of 49.3 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: ANPRB
ANPRB(Arg23-Ile458) 6×His tag:: ANPRB(Arg23-Ile458) 6×His tag
Extra Details:: This gene encodes natriuretic peptide receptor B; one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain; a single membrane-spanning region; and intracellularly a protein kinase homology domain; a helical hinge region involved in oligomerization; and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP); which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq; Jul 2008]

Shipping Conditions:: Ambient