Human BTK Protein; Flag Tag

Size

£174.00

SKU:: PME101186
Additional Names:: AGMX1;AT;ATK;BPK;IGHD3;IMD1;PSCTK1;XLA
Molecular Weight:: The protein has a predicted molecular mass of 79.2 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: BTK
BTK(Met1-Ser659) 3×Flag tag:: BTK(Met1-Ser659) 3×Flag tag
Extra Details:: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1; which is an immunodeficiency characterized by the failure to produce mature B lymphocytes; and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq; Dec 2013]