PME101122
Human PTPRG Protein; hFc Tag
Size
£199.00
- SKU:
- PME101122
- Additional Names:
- PTPG; HPTPG; RPTPG; R-PTP-GAMMA
- Molecular Weight:
- The protein has a predicted molecular mass of 104.9 kDa after removal of the signal peptide.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- PTPRG
- PTPRG(Val20-Glu736) hFc(Glu99-Ala330):
- PTPRG(Val20-Glu736) hFc(Glu99-Ala330)
- Extra Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitotic cycle; and oncogenic transformation. This PTP possesses an extracellular region; a single transmembrane region; and two tandem intracytoplasmic catalytic domains; and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain; which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma; thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq; Jul 2008]
- Shipping Conditions:
- Ambient