PME101092
Human HGF Protein; hFc Tag
Size
£181.00
- SKU:
- PME101092
- Additional Names:
- DFNB39;F-TCF;HGFB;HPTA;SF
- Molecular Weight:
- The protein has a predicted molecular mass of 105.8 kDa after removal of the signal peptide.The apparent molecular mass of HGF-hFc is approximately 100-130 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- HGF
- HGF(Gln32-Ser728) hFc(Glu99-Ala330):
- HGF(Gln32-Ser728) hFc(Glu99-Ala330)
- Extra Details:
- This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth; cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants; at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains; which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis; tumorogenesis; and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases; it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. [provided by RefSeq; Nov 2015]
- Shipping Conditions:
- Ambient