PME101072
Human TIE2 Protein; hFc Tag
Size
£171.00
- SKU:
- PME101072
- Additional Names:
- CD202B;GLC3E;TIE-2;TIE2;VMCM;VMCM1
- Molecular Weight:
- The protein has a predicted molecular mass of 105.38 kDa after removal of the signal peptide.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- TIE2
- TIE2 (Trp23-Leu748) hFc(Glu99-ALA330):
- TIE2 (Trp23-Leu748) hFc(Glu99-ALA330)
- Extra Details:
- This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains; three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described; but their full-length nature is not known. [provided by RefSeq; Feb 2014]
- Shipping Conditions:
- Ambient