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PME101071

Human CD305 Protein; hFc Tag

Size

£171.00

SKU:
PME101071
Additional Names:
CD305;LAIR-1
Molecular Weight:
The protein has a predicted molecular mass of 41.36 kDa after removal of the signal peptide.
Purity:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
DIMA Biotechnology Ltd
Formulation:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
CD305
CD305 (Gln22-Y165) hFc(Glu99-ALA330):
CD305 (Gln22-Y165) hFc(Glu99-ALA330)
Extra Details:
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells; including natural killer cells; T cells; and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster; which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1; and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Jan 2014]
Shipping Conditions:
Ambient