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PME101003

Human ROBO1 Protein; hFc Tag

Size

£219.00

SKU:
PME101003
Additional Names:
Deleted in U twenty twenty;H-Robo-1
Molecular Weight:
The protein has a predicted molecular mass of 121.8 kDa after removal of the signal peptide. The apparent molecular mass of ROBO1-hFc is approximately 100-130 kDa due to glycosylation.
Purity:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
DIMA Biotechnology Ltd
Formulation:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
ROBO1
ROBO1(Gln26-Pro897) hFc(Glu99-Ala330):
ROBO1(Gln26-Pro897) hFc(Glu99-Ala330)
Extra Details:
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins; resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Mar 2009]
Shipping Conditions:
Ambient