PME101000
Human PTGER4 Protein; hFc Tag
Size
£202.00
- SKU:
- PME101000
- Additional Names:
- EP4;EP4R
- Molecular Weight:
- The protein has a predicted molecular mass of 28.1 kDa after removal of the signal peptide. The apparent molecular mass of PTGER4-hFc is approximately 35-55 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- PTGER4
- PTGER4(Met1-Ser19) hFc(Glu99-Ala330):
- PTGER4(Met1-Ser19) hFc(Glu99-Ala330)
- Extra Details:
- The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1); regulate the level and stability of cyclooxygenase-2 mRNA; and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system; osteoporosis; as well as initiation of skin immune responses. [provided by RefSeq; Jul 2008]
- Shipping Conditions:
- Ambient