Human PRAME Protein; hFc Tag

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£171.00

SKU:: PME100998
Additional Names:: CT130;MAPE;OIP-4;OIP4
Molecular Weight:: The protein has a predicted molecular mass of 81.51 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: PRAME
PRAME (Met1-Asn509) hFc (Glu99-Ala330):: PRAME (Met1-Asn509) hFc (Glu99-Ala330)
Extra Details:: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues; except testis. The encoded protein acts as a repressor of retinoic acid receptor; and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Apr 2014]