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PME100977

Human MERTK Protein; hFc Tag

Size

£171.00

SKU:
PME100977
Additional Names:
Tyrosine-protein kinase Mer;Proto-oncogene c-Mer;Receptor tyrosine kinase MerTK
Molecular Weight:
The protein has a predicted molecular mass of 78.8 kDa after removal of the signal peptide. The apparent molecular mass of MERTK-hFc is approximately 100-130 kDa due to glycosylation.
Purity:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
DIMA Biotechnology Ltd
Formulation:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
MERTK
MERTK(Ala21-Ile505) hFc(Glu99-Ala330):
MERTK(Ala21-Ile505) hFc(Glu99-Ala330)
Extra Details:
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains; two Ig-like C2-type (immunoglobulin-like) domains; and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq; Jul 2008]
Shipping Conditions:
Ambient