Human IFNAR2 Protein; hFc Tag

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£171.00

SKU:: PME100959
Additional Names:: IFN-alpha-REC;IFN-R;IFNABR;IFNARB;IMD45
Molecular Weight:: The protein has a predicted molecular mass of 50.9 kDa after removal of the signal peptide. The apparent molecular mass of IFNAR2-hFc is approximately 55-70 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: IFNAR2
IFNAR2(Ile27-Lys243) hFc(Glu99-Ala330):: IFNAR2(Ile27-Lys243) hFc(Glu99-Ala330)
Extra Details:: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases; which in turn phosphorylate several proteins; including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45. [provided by RefSeq; Jul 2020]