PME100874
Human Nectin-4 Protein; His Tag
Size
£171.00
- SKU:
- PME100874
- Additional Names:
- EDSS1;LNIR;nectin-4;PRR4;PVRL4
- Molecular Weight:
- The protein has a predicted molecular mass of 34.9 kDa after removal of the signal peptide.The apparent molecular mass of Nectin-4-His is approximately 35-55 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- Nectin-4
- Nectin-4(Gly32-Ser349) 6×His Tag:
- Nectin-4(Gly32-Ser349) 6×His Tag
- Extra Details:
- This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1; an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq; Jan 2011]
- Shipping Conditions:
- Ambient