Human FOLR2 Protein; hFc Tag

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£180.00

SKU:: PME100868
Additional Names:: BETA-HFR;FBP;FBP/PL-1;FOLR1;FR-BETA;FR-P3;FRbeta
Molecular Weight:: The protein has a predicted molecular mass of 50.7 kDa after removal of the signal peptide. The apparent molecular mass of FOLR2-hFc is approximately 55-70 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: FOLR2
FOLR2(Thr17-His228) hFc(Glu99-Ala330):: FOLR2(Thr17-His228) hFc(Glu99-Ala330)
Extra Details:: The protein encoded by this gene is a member of the folate receptor (FOLR) family; and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives; and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins; respectively. Although this protein was originally thought to be specific to placenta; it can also exist in other tissues; and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq; Jul 2008]

Shipping Conditions:: Ambient