PME100860
Human CD4 Protein; hFc Tag
Size
£171.00
- SKU:
- PME100860
- Additional Names:
- CD4;D4mut;EU3
- Molecular Weight:
- The protein has a predicted molecular mass of 65.67 kDa after removal of the signal peptide.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- CD4
- CD4(Lys26-Trp390) hFc(Glu99-Ala330):
- CD4(Lys26-Trp390) hFc(Glu99-Ala330)
- Extra Details:
- This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes; but also in B cells; macrophages; granulocytes; as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation; and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
- Shipping Conditions:
- Ambient