PME100853
Human TNFRSF11A Protein; hFc Tag
Size
£171.00
- SKU:
- PME100853
- Additional Names:
- Tumor necrosis factor receptor superfamily member 11A;ODFR;Receptor activator of NF-KB;CD265;RANK
- Molecular Weight:
- The protein has a predicted molecular mass of 46.2 kDa after removal of the signal peptide. The apparent molecular mass of TNFRSF11A-hFc is approximately 55-70 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- TNFRSF11A
- TNFRSF11A(Ile30-Pro212) hFc(Glu99-Ala330):
- TNFRSF11A(Ile30-Pro212) hFc(Glu99-Ala330)
- Extra Details:
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins; through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis; autosomal recessive osteopetrosis; and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq; Aug 2012]
- Shipping Conditions:
- Ambient