Human IL17RB Protein; hFc Tag

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£171.00

SKU:: PME100837
Additional Names:: CRL4;EVI27;IL17BR;IL17RH1
Molecular Weight:: The protein has a predicted molecular mass of 55.77 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: IL17RB
IL17RB (Arg18-Pro292) hFc(Glu99-Ala330):: IL17RB (Arg18-Pro292) hFc(Glu99-Ala330)
Extra Details:: The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E; but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation; which suggested the immunoregulatory activity of this receptor.