PME100825
Human CCR7 Protein; hFc Tag
Size
£177.00
- SKU:
- PME100825
- Additional Names:
- BLR2;CC-CKR-7;CCR-7;CD197;CDw197;CMKBR7;EBI1
- Molecular Weight:
- The protein has a predicted molecular mass of 30.2 kDa after removal of the signal peptide. The apparent molecular mass of CCR7-hFc is approximately 35-55 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- CCR7
- CCR7(Gln25-Trp59) hFc(Glu99-Ala330):
- CCR7(Gln25-Trp59) hFc(Glu99-Ala330)
- Extra Details:
- The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV); and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues; as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes; and may also function in the activation and polarization of T cells; and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq; Sep 2014]
- Shipping Conditions:
- Ambient