Human MST1R Protein; hFc Tag

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£236.00

SKU:: PME100821
Additional Names:: CD136;CDw136;NPCA3;PTK8;RON
Molecular Weight:: The protein has a predicted molecular mass of 125.9 kDa after removal of the signal peptide. The apparent molecular mass of MST1R-hFc is approximately 130-250 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: MST1R
MST1R(Glu25-Thr957) hFc(Glu99-Ala330):: MST1R(Glu25-Thr957) hFc(Glu99-Ala330)
Extra Details:: This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits; generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung; and together with MSP; thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq; Jan 2016]

Shipping Conditions:: Ambient