PME100808
Human ITGAM Protein; hFc Tag
Size
£199.00
- SKU:
- PME100808
- Additional Names:
- CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6
- Molecular Weight:
- The protein has a predicted molecular mass of 146.6 kDa after removal of the signal peptide.
- Purity:
- The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- ITGAM
- ITGAM(Phe17-Asn1104) hFc(Glu99-Ala330):
- ITGAM(Phe17-Asn1104) hFc(Glu99-Ala330)
- Extra Details:
- This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'); or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium; and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Mar 2009]
- Shipping Conditions:
- Ambient