Human TREM1 Protein; hFc Tag

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£202.00

SKU:: PME100797
Additional Names:: TREM-1;CD354
Molecular Weight:: The protein has a predicted molecular mass of 46.4 kDa after removal of the signal peptide. The apparent molecular mass of TREM1-hFc is approximately 55-70 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: TREM1
TREM1(Ala21-Arg200) hFc(Glu99-Ala330):: TREM1(Ala21-Arg200) hFc(Glu99-Ala330)
Extra Details:: This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines; as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq; Jun 2011]